Article
Contribution of Candida albicans ALS1 to the pathogenesis of experimental oropharyngeal candidiasis.
Infection and immunity - 1 Sept 2002
Kamai Yasuki, Kubota Mikie, Kamai Yoko, Hosokawa Tsunemichi, Fukuoka Takashi, Filler Scott G
Abstract excerpt
We investigated the contribution of Candida albicans ALS1, which encodes a candidal adhesin, to the pathogenesis of experimental murine oropharyngeal candidiasis. Our results indicate that the ALS1 gene product is important for the adherence of the organism to the oral mucosa during the early stage of the infection.
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