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The Candida Albicans Agglutinin-Like Sequence Family of Adhesins: Functional Insights Gained from Structural Analysis

1 Oct 2015

Abstract excerpt

Candida albicans colonizes many host sites suggesting its interaction with diverse ligands. Candida albicans adhesion is mediated by a number of proteins including those in the Als (agglutinin-like sequence) family, which have been studied intensively. The recent solution of the Als binding domain structure ended years of speculation regarding the molecular mechanism for Als adhesive function. Als adhesins bind...

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PMID: 26438189
DOI: 10.2217/fmb.15.79

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