Article
Deletion of<i>ALS5</i>,<i>ALS6</i>or<i>ALS7</i>increases adhesion of<i>Candida albicans</i>to human vascular endothelial and buccal epithelial cells
1 Jan 2007
Abstract excerpt
Candida albicans yeast forms deleted for ALS5, ALS6 or ALS7 are more adherent than a relevant control strain to human vascular endothelial cell monolayers and buccal epithelial cells. In the buccal and vaginal reconstituted human epithelium (RHE) disease models, however, mutant and control strains caused a similar degree of tissue destruction. Deletion of ALS5 or ALS6 significantly slowed growth of the mutant...
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