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Article

Analysis of the Candida albicans Als2p and Als4p adhesins suggests the potential for compensatory function within the Als family

1 May 2005

Abstract excerpt

The ALS (agglutinin-like sequence) gene family encodes eight large cell-surface glycoproteins. The work presented here focuses on Als2p and Als4p, and is part of a larger effort to deduce the function of each Als protein. Both ALS4 alleles were deleted from the Candida albicans genome and the phenotype of the mutant strain (als4Delta/als4Delta; named 2034) studied. Loss of Als4p slowed germ tube formation of...

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PMID: 15870470
DOI: 10.1099/mic.0.27763-0

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