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Article

Saccharomyces forkhead protein Fkh1 regulates donor preference during mating-type switching through the recombination enhancer.

Genes & development - 15 Aug 2002

Sun Kaiming, Coïc Eric, Zhou Zhiqi, Durrens Pascal, Haber James E

Abstract excerpt

Saccharomyces mating-type switching results from replacement by gene conversion of the MAT locus with sequences copied from one of two unexpressed donor loci, HML or HMR. MATa cells recombine with HMLalpha approximately 90% of the time, whereas MATalpha cells choose HMRa 80%-90% of the time. HML preference in MATa is controlled by the cis-acting recombination enhancer (RE) that regulates recombination along the...

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PMID: 12183363
DOI: 10.1101/gad.994902
PMCID: PMC186439

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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