Article
The effect of reproductive compensation on recessive disorders within consanguineous human populations.
Heredity - 1 Jun 2002
Overall A D J, Ahmad M, Nichols R A
Abstract excerpt
We investigate the effects of consanguinity and population substructure on genetic health using the UK Asian population as an example. We review and expand upon previous treatments dealing with the deleterious effects of consanguinity on recessive disorders and consider how other factors, such as population substructure, may be of equal importance. For illustration, we quantify the relative risks of recessive...
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