Article
Reproductive compensation and human genetic disease.
Genetical research - 1 Jun 2001
Hastings I M
Abstract excerpt
The effects of reproductive compensation on the population genetics of sex-linked recessive lethal mutations are investigated. Simple equations are presented which describe these effects, and so complement existing population genetic theory. More importantly, this type of mutation is responsible for several severe human genetic diseases such as Duchenne muscular dystrophy. It is argued that the applications of...
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