Article
CD26 expression in mature B-cell neoplasia: its possible role as a new prognostic marker in B-CLL.
Hematological oncology - 1 Sept 2009
Cro Lilla, Morabito Fortunato, Zucal Nadia, Fabris Sonia, Lionetti Marta, Cutrona Giovanna, Rossi Francesca, Gentile Massimo, Ferrario Andrea, Ferrarini Manlio, Molica Stefano, Neri Antonino, Baldini Luca
Abstract excerpt
CD26 (dipeptidyl peptidase IV, DPP IV) is widely expressed by T and natural killer (NK) cells, epithelial and endothelial cells of different tissues, and it is strongly upregulated in activated B-cells; moreover it plays a regulatory role in the neoplastic transformation and progression of various types of tumours. CD26 expression was evaluated by means of flow cytometry in various peripheral B-cell lymphoid...
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