Article
Cytochrome P450 2E1 genetic polymorphism and gastric cancer in Changle, Fujian Province.
World journal of gastroenterology - 1 Dec 2001
Cai L, Yu S Z, Zhan Z F
Abstract excerpt
AIM: Genetic polymorphism in enzymes of carcinogen metabolism has been found to have the influence on the susceptibility to cancer. Cytochrome P450 2E1 (CYP2E1) is considered to play an important role in the metabolic activation of procarcinogens such as N-nitrosoamines and low molecular weight organic compounds. The purpose of this study is to determine whether CYP450 2E1 polymorphisms are associated with risks...
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