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Article

Cytochrome p450 2E1 polymorphisms and the risk of gastric cardia cancer.

World journal of gastroenterology - 28 Mar 2005

Cai Lin, Zheng Zong-Li, Zhang Zuo-Feng

Abstract excerpt

AIM: Genetic polymorphisms of drug-metabolizing enzymes have recently been shown to affect susceptibility to chemical carcinogenesis. Cytochrome P450 2E1 (CYP2E1) enzyme catalyzes the metabolism of many procarcinogens, such as N-nitrosamines and related compounds. The gene coding for this enzyme is polymorphic and thus may play a role in gastric cardia cancer (GCC) etiology. In this hospital-based case-control...

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Identifiers

PMID: 15793883
DOI: 10.3748/wjg.v11.i12.1867
PMCID: PMC4305893

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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