Article
Human Herpesvirus 6 and Measles Virus Employ Distinct CD46 Domains for Receptor Function
1 Oct 2002
Abstract excerpt
We employed a quantitative cell fusion assay to identify structural domains of CD46 required for its function as a receptor for human herpesvirus 6 (HHV-6). We examined the activities of recombinant variants of CD46, including different isoforms as well as engineered truncations and molecular chimeras with decay-accelerating factor, a related protein in the family of regulators of complement activation (RCA). We...
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