Article
Diversity of sites for measles virus binding and for inactivation of complement C3b and C4b on membrane cofactor protein CD46.
The Journal of biological chemistry - 23 Jun 1995
Iwata K, Seya T, Yanagi Y, Pesando J M, Johnson P M, Okabe M, Ueda S, Ariga H, Nagasawa S
Abstract excerpt
The complement system membrane cofactor protein (MCP) CD46 serves as a C3b/C4b inactivating factor for the protection of host cells from autologous complement attack and as a receptor for measles virus (MV). MCP consists of four short consensus repeats (SCR) which are the predominant extracellula...
Topics
- Animals
- Antibodies, Monoclonal
- Antigens, CD
- Base Sequence
- CHO Cells
- Complement C3b
- Complement C3b Inactivator Proteins
- Complement C4b
- Complement Pathway, Alternative
- Complement Pathway, Classical
- Consensus Sequence
- Cricetinae
- DNA, Complementary
- Epitopes