Article
Quantitative selection constants.
Cancer biology & therapy - 1 Jan 2000
Kern Scott E
Abstract excerpt
The study of the genetics of human tumors produces numerical data concerning the frequencies of mutation of individual genes. These frequencies are dependent on a number of processes that act individually and differentially upon genes, and can in turn be conceptualized in quantitative terms to encompass the rates of random mutations within cells, the efficiencies of the evolution of initial mutations to produce...
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