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Article

Molecular and genetic characterization of a non-metastatic human esophageal cancer cell line, T.Tn expressing non-functional mutated p53.

International journal of oncology - 1 Sept 2002

Sakai Taro, Furihata Tadashi, Kawamata Hitoshi, Omotehara Fumie, Shinagawa Yasuhiro, Imura Johji, Kubota Keiichi, Terano Akira, Fujimori Takahiro

Abstract excerpt

Lymph node metastasis is commonly found in esophageal squamous cell carcinoma (SCC). In this study, we examined the molecular and genetic characteristics of a human esophageal SCC cell line, T.Tn. T.Tn cells formed tumors at s.c. tissue in nude mice when inoculated with Matrigel, but did not metastasize to any organs. T.Tn cells expressed low level of proMMP2 and a trace level of proMMP9. However, T.Tn cells...

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PMID: 12168098

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CAT
MDM2
TIMP1
TIMP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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