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Article

Combinatorial diversity of fission yeast SCF ubiquitin ligases by homo- and heterooligomeric assemblies of the F-box proteins Pop1p and Pop2p.

BMC biochemistry - 7 Aug 2002

Seibert Volker, Prohl Corinna, Schoultz Ida, Rhee Edward, Lopez Rebecca, Abderazzaq Kareem, Zhou Chunshui, Wolf Dieter A

Abstract excerpt

BACKGROUND: SCF ubiquitin ligases share the core subunits cullin 1, SKP1, and HRT1/RBX1/ROC1, which associate with different F-box proteins. F-box proteins bind substrates following their phosphorylation upon stimulation of various signaling pathways. Ubiquitin-mediated destruction of the fission yeast cyclin-dependent kinase inhibitor Rum1p depends on two heterooligomerizing F-box proteins, Pop1p and Pop2p. Both...

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Source

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Identifiers

PMID: 12167173
DOI: 10.1186/1471-2091-3-22
PMCID: PMC128837

Genes

RBX1
SKP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Combinatorial diversity of fission yeast SCF ubiquitin ligases by homo- and heterooligomeric assemblies of the F-box proteins Pop1p and Pop2p.PMID 12167173Read ↗

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