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Article

RING finger specificity in SCF-driven protein destruction.

Developmental cell - 1 Jun 2002

Jin Jianping, Harper J Wade

Abstract excerpt

SCF ubiquitin ligases contain an E3 core composed of Skp1, Cul1, a member of the Rbx1/Roc1 family of RING finger proteins, and a modular F box protein that functions in substrate targeting. Work published in this issue of Developmental Cell indicates that distinct Rbx1/Roc1 family members are used to control ubiquitination of distinct targets, suggesting that the RING finger subunit may contribute to...

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Identifiers

PMID: 12062077
DOI: 10.1016/s1534-5807(02)00194-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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