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Article

Differential expression of the mannose 6-phosphate/ insulin-like growth factor-II receptor in human breast cancer cell lines of different invasive potential.

Medical science monitor : international medical journal of experimental and clinical research - 1 Aug 2002

Xie Suqing, Kang Jing X

Abstract excerpt

BACKGROUND: Hypersecretion of the precursor of the lysosomal protease cathepsin D (procathepsin D) has been implicated in the invasive phenotype of human breast cancer. However, the mechanism of the abnormal secretion of procathepsin D remains unclear. Since the mannose 6-phosphate/insulin-like growth factor II receptor (M6P/IGF2R) plays a central role in the intracellular transport and endocytosis of...

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PMID: 12165733

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Differential expression of the mannose 6-phosphate/ insulin-like growth factor-II receptor in human breast cancer cell lines of different invasive potential.PMID 12165733Read ↗

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Human IGF1 pro-forms induce breast cancer cell proliferation via the IGF1 receptorSemantic proximity Read ↗

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