Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Type-2 IGF receptor: a multi-ligand binding protein.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme - 1 Jan 2000

Braulke T

Abstract excerpt

The Type-2 insulin-like growth factor receptor (IGF2R) is a ubiquitously expressed integral glycoprotein with a molecular mass of 300 kDa. Four different classes of ligands are presently known, binding to distinct sites at the extracytoplasmic receptor domain: mannose 6-phosphate-containing lysosomal enzymes, the non-glycosylated IGF II, retinoic acid, and urokinase-type plasminogen activator receptor. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Mutation
Share to Receptor, IGF Type 2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10226808
DOI: 10.1055/s-2007-978725

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Type-2 IGF receptor: a multi-ligand binding protein.PMID 10226808Read ↗

Insulin-like growth factor-2/mannose-6 phosphate receptors.Semantic proximity Read ↗

The Role of Insulin-Like Growth Factor 2 and Its Receptors in Human TumorsSemantic proximity Read ↗

Mannose-6-phosphate/Insulin-like Growth Factor II Receptor Expression and Tumor DevelopmentSemantic proximity Read ↗

The Role of the IGF System in Cancer Growth and Metastasis: Overview and Recent InsightsSemantic proximity Read ↗

Insulin-like growth factor II (IGF-II).Semantic proximity Read ↗

Insulin Receptor Isoforms and Insulin Growth Factor-like Receptors: Implications in Cell Signaling, Carcinogenesis, and ChemoresistanceSemantic proximity Read ↗

The Role of the IGF System in Cancer: From Basic to Clinical Studies and Clinical ApplicationsSemantic proximity Read ↗

Role of Insulin-Like Growth Factor Receptor 2 across Muscle Homeostasis: Implications for Treating Muscular DystrophySemantic proximity Read ↗

Insulin‐like growth factor ligands, receptors, and binding proteins in cancerSemantic proximity Read ↗

Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds.Semantic proximity Read ↗

The Effects of Insulin-Like Growth Factors on Tumorigenesis and Neoplastic GrowthSemantic proximity Read ↗

IGF2: epigenetic regulation and role in development and disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.