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Article

Ghrelin gene: identification of missense variants and a frameshift mutation in extremely obese children and adolescents and healthy normal weight students.

The Journal of clinical endocrinology and metabolism - 1 Jun 2002

Hinney Anke, Hoch Anne, Geller Frank, Schäfer Helmut, Siegfried Wolfgang, Goldschmidt Hanspeter, Remschmidt Helmut, Hebebrand Johannes

Abstract excerpt

Ghrelin induces obesity via central and peripheral mechanisms. Administration of ghrelin leads to increased food intake and decreased fat utilisation in rodents. Ghrelin levels are decreased in obese individuals. Recently, a polymorphism (Arg-51-Gln) within the ghrelin gene (GHRL) was described t...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12050239
DOI: 10.1210/jcem.87.6.8672

Genes

GHRL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12050239-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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