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Article

Role of genetic background in P selectin-dependent immune surveillance of the central nervous system.

Journal of neuroimmunology - 1 Aug 2002

Carrithers Michael D, Visintin Irene, Viret Christophe, Janeway Charles S

Abstract excerpt

Although the blood-brain barrier and blood cerebrospinal fluid barrier maintain the central nervous system (CNS) as an immunologically privileged site, T lymphocytes can migrate through unstimulated brain endothelium and epithelium to perform immune surveillance or initiate inflammation. Our prior results suggested that early CNS migration of a CD4 Th1 cell line was facilitated by P selectin (CD62P) in...

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Identifiers

PMID: 12161020
DOI: 10.1016/s0165-5728(02)00172-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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