Article
Altered expression and loss of heterozygosity of the migration and invasion inhibitory protein (MIIP) gene in breast cancer.
Oncology reports - 1 Jun 2015
Song Fangfang, Zhang Ling, Ji Ping, Zheng Hong, Zhao Yanrui, Zhang Wei, Chen Kexin
Abstract excerpt
Previous studies have characterized the migration and invasion inhibitory protein (MIIP) as a novel putative tumor-suppressor gene that regulates cell migration and invasion as well as the mitotic checkpoint. The MIIP gene is located on chromosome 1p36.22, a common site for deletion in many solid tumors including breast cancer. In the present study, we evaluated MIIP expression and allelic deletion to gain...
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