Article
Dominance of functional androgen receptor allele with longer CAG repeat in hepatitis B virus-related female hepatocarcinogenesis.
Cancer research - 1 Aug 2002
Yeh Shiou-Hwei, Chang Ching-Fung, Shau Wen-Yi, Chen Ya-Wen, Hsu Hey-Chi, Lee Po-Huang, Chen Ding-Shinn, Chen Pei-Jer
Abstract excerpt
The CAG polymorphism in exon 1 of the androgen receptor (AR) gene has been shown associated with the development of human male hepatocellular carcinoma (HCC) with the shorter AR alleles conferring a higher risk. However, the significance of AR-CAG repeats in female hepatocarcinogenesis remains to be addressed. In this study, seventy-six pairs of female HCCs and corresponding nontumorous tissues were collected,...
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