Article
The polyglycine and polyglutamine repeats in the androgen receptor gene in Japanese and Caucasian populations.
Biochemical and biophysical research communications - 26 Dec 2003
Sasaki Masahiro, Kaneuchi Masanori, Sakuragi Noriaki, Fujimoto Seiichiro, Carroll Peter R, Dahiya Rajvir
Abstract excerpt
Human androgen receptor (AR) gene contains two polymorphic trinucleotide repeats of CAG and GGC, which code for polyglutamine and polyglycine tracts in the N-terminal domain in which the receptor activity resides. Longer repeats induce decrease of transactivation function in the AR receptor, weak...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
