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Article

Retrovirus-mediated herpes simplex virus thymidine kinase gene transfer in pancreatic cancer cell lines: an incomplete antitumor effect.

Pancreas - 1 Aug 2002

Greco Eliana, Fogar Paola, Basso Daniela, Stefani Anna Lisa, Navaglia Filippo, Zambon Carlo-Federico, Mazza Saverio, Gallo Nicoletta, Piva Maria Grazia, Scarpa Aldo, Pedrazzoli Sergio, Plebani Mario

Abstract excerpt

INTRODUCTION: The transfer of drug-susceptible (suicide) genes to tumor cells by retroviral or adenoviral vectors is a novel approach to the treatment of human tumors. AIMS: To ascertain the antitumor effect of retroviral transduction of the pancreatic cancer cell lines MIA PaCa 2, CAPAN-1, PANC1, and PSN1 with the herpes simplex virus thymidine kinase (HSV-TK) gene. METHODOLOGY: The vector carried a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12142751
DOI: 10.1097/00006676-200208000-00020

Genes

MIA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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