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Article

Oncolytic viral therapy for human pancreatic cancer cells by reovirus.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2003

Etoh Tsuyoshi, Himeno Yoshihisa, Matsumoto Toshifumi, Aramaki Masanori, Kawano Katsunori, Nishizono Akira, Kitano Seigo

Abstract excerpt

PURPOSE: Pancreatic cancer has a poor prognosis and few effective therapies are available. The oncolytic effect of reovirus has been observed in cancer cells with an activated Ras signaling pathway, and pancreatic cancer may be a candidate target for reovirus because K-ras mutation is frequently found in pancreatic cancer. EXPERIMENTAL DESIGN: In this study, we examined the feasibility of using reovirus (serotype...

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PMID: 12631628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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