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Article

Herpes simplex virus thymidine kinase and ganciclovir suicide gene therapy for human pancreatic cancer

1 Jan 2004

Abstract excerpt

AIM: To investigate the in vitro effects of suicide gene therapy system of herpes simplex virus thymidine kinase gene (HSV-TK) in combination with the treatment of nucleotide analog-ganciclovir (GCV) on human pancreatic cancer, and to provide a novel clinical therapeutic method for human pancreatic cancer. METHODS: We used a replication defective recombinant retrovirus vector GINaTK (bearing HSV-TK gene) to make...

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Identifiers

PMID: 14760766
DOI: 10.3748/wjg.v10.i3.400

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