Missing HLA class I expression on Daudi cells unveils cytotoxic and proliferative responses of human gammadelta T lymphocytes.

doi:10.1016/s0008-8749(02)00001-1

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Article

Missing HLA class I expression on Daudi cells unveils cytotoxic and proliferative responses of human gammadelta T lymphocytes.

Cellular immunology - 1 Jan 2002

Rothenfusser Simon, Buchwald Armin, Kock Sylvia, Ferrone Soldano, Fisch Paul

Abstract excerpt

The major subset of human blood gammadelta T lymphocytes expresses the variable-region genes Vgamma9 and Vdelta2. These cells recognize non-peptidic phosphoantigens that are present in some microbial extracts, as well as the beta(2)-microglobulin-deficient Burkitt's lymphoma Daudi. Most cytotoxic human Vgamma9/Vdelta2 T cells express inhibitory natural killer cell receptors for HLA class I that downmodulate the...

Topics

Alleles
Cells, Cultured
Clone Cells
Cytotoxicity, Immunologic
HLA Antigens
Histocompatibility Antigens Class I
Humans
Hybridomas
Immunoglobulin Variable Region
Neoplasms
Receptors, Antigen, T-Cell, gamma-delta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Immunologic

Receptors, KIR

T-Lymphocytes

T-Lymphocytes, Cytotoxic

Tumor Cells, Cultured

beta 2-Microglobulin

Source

Open in PubMed

Identifiers

PMID: 12142034
DOI: 10.1016/s0008-8749(02)00001-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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