Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NKG2A inhibits NKG2C effector functions of γδ T cells: implications in health and disease.

Journal of leukocyte biology - 1 Jan 2011

Angelini Daniela F, Zambello Renato, Galandrini Ricciarda, Diamantini Adamo, Placido Roberta, Micucci Federica, Poccia Fabrizio, Semenzato Giuseppe, Borsellino Giovanna, Santoni Angela, Battistini Luca

Abstract excerpt

The CD94/NKG2 complex is expressed on T and NK lymphocytes. CD94 molecules covalently associate to activating or inhibitory NKG2 molecules, and their expression finely tunes cell responses. Human γδ T cells express several NKRs. Expression of these receptors is confined to the cytolytic Vδ2 subset, which coexpresses the FcγRIII CD16 and CD45RA and has been defined as Vγ9Vδ2 T(EMRA) cells. We show that the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clone Cells
Share to Cross-Linking Reagents

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Health

Share to Killer Cells, Natural

Share to Leukemia, Large Granular Lymphocytic

Share to NK Cell Lectin-Like Receptor Subfamily C

Share to Receptors, Antigen, T-Cell, gamma-delta

Share to Tissue Donors

Source

Identifiers

PMID: 20952657
DOI: 10.1189/jlb.0710413

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NKG2A inhibits NKG2C effector functions of γδ T cells: implications in health and disease.PMID 20952657Read ↗

Relationship of NKG2C Copy Number with the Distribution of Distinct Cytomegalovirus-Induced Adaptive NK Cell SubsetsSemantic proximity Read ↗

Rat and mouse CD94 associate directly with the activating transmembrane adaptor proteins DAP12 and DAP10 and activate NK cell cytotoxicity.Semantic proximity Read ↗

NKG2D Receptor and Its Ligands in Host DefenseSemantic proximity Read ↗

Downregulation of CD94/NKG2A inhibitory receptor on decreased γδ T cells in patients with systemic lupus erythematosus.Semantic proximity Read ↗

Human NKG2E is expressed and forms an intracytoplasmic complex with CD94 and DAP12.Semantic proximity Read ↗

Functional inhibitory human leucocyte antigen class I receptors on natural killer (NK) cells in patients with chronic NK lymphocytosis.Semantic proximity Read ↗

A Truncated Human NKG2D Splice Isoform Negatively Regulates NKG2D-Mediated FunctionSemantic proximity Read ↗

NKG2A/CD94 Is a New Immune Receptor for HLA-G and Distinguishes Amino Acid Differences in the HLA-G Heavy Chain.Semantic proximity Read ↗

Polygenic polymorphism is associated with NKG2A repertoire and influences lymphocyte phenotype and function.Semantic proximity Read ↗

Advances in NKG2D ligand recognition and responses by NK cellsSemantic proximity Read ↗

FcgammaRIII discriminates between 2 subsets of Vgamma9Vdelta2 effector cells with different responses and activation pathways.Semantic proximity Read ↗

Altered NK-cell compartment and dysfunctional NKG2D/NKG2D-ligand axis in patients with ataxia-telangiectasia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.