Article
FcgammaRIII discriminates between 2 subsets of Vgamma9Vdelta2 effector cells with different responses and activation pathways.
Blood - 15 Sept 2004
Angelini Daniela F, Borsellino Giovanna, Poupot Mary, Diamantini Adamo, Poupot Rémy, Bernardi Giorgio, Poccia Fabrizio, Fournié Jean-Jacques, Battistini Luca
Abstract excerpt
Upon recognition of nonpeptidic phosphoantigens, human Vdelta2 T lymphocytes enter a lineage differentiation pattern that determines the generation of memory cells with a range of effector functions. Here, we show that within the effector memory Vdelta2 population, 2 distinct and complementary subsets with regard to phenotype, mode of activation, and type of responses can be identified: Vdelta2 T(EMh) cells,...
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