Article
Exogenous Slit2 does not affect ureteric branching or nephron formation during kidney development.
The International journal of developmental biology - 1 Jan 2002
Piper Michael, Nurcombe Victor, Wilkinson Lorine, Little Melissa
Abstract excerpt
In an attempt to elucidate the role of Slit2 in vertebrate kidney development, the effect of adding exogenous human Slit2 protein (hSlit2) to developing murine metanephric kidney explants was examined. To confirm the activity of the recombinant Slit2 protein, neurons from 8 day old chick sympathetic nerve chain dorsal root ganglia were cultured with hSlit2 protein, which induced significant neurite branching and...
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