Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel strategy for defining haplotypes by selective depletion using restriction enzymes.

Immunogenetics - 1 Jan 2007

Smirnova Anna S, Ferreira-Silva Kátia C, Mine Karina L, Andrade-Oliveira Vinicius, Shulzhenko Natalia, Gerbase-DeLima Maria, Morgun Andrey

Abstract excerpt

Various single nucleotide polymorphisms (SNPs) have been investigated regarding association with gene expression levels or human diseases. Although different SNPs within one gene are frequently analyzed individually, it is highly probable that in the majority of the cases, a precise combination of SNP alleles, i.e., haplotype, determines a functional trait. Methods commonly used for haplotype determination,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Brazil
Share to DNA Restriction Enzymes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Testing

Share to Genotype

Share to Haplotypes

Share to Polymerase Chain Reaction

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 17146685
DOI: 10.1007/s00251-006-0172-8

Genes

LTA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel strategy for defining haplotypes by selective depletion using restriction enzymes.PMID 17146685Read ↗

An efficient haplotyping method with DNA pools.Semantic proximity Read ↗

Haplotyping by double PCR amplification of specific alleles.Semantic proximity Read ↗

Molecular haplotyping of genomic DNA for multiple single-nucleotide polymorphisms located kilobases apart using long-range polymerase chain reaction and intramolecular ligation.Semantic proximity Read ↗

A better block partition and ligation strategy for individual haplotyping.Semantic proximity Read ↗

Direct haplotyping of bi-allelic SNPs using ARMS and RFLP analysis techniques.Semantic proximity Read ↗

Direct micro-haplotyping by multiple double PCR amplifications of specific alleles (MD-PASA).Semantic proximity Read ↗

Haplotype-specific extraction: a universal method to resolve ambiguous genotypes and detect new alleles - demonstrated on HLA-B.Semantic proximity Read ↗

Use of DNA haplotype analysis in diagnosis of familial hypercholesterolaemia in 31 German families.Semantic proximity Read ↗

Direct molecular haplotyping by melting curve analysis of hybridization probes: beta 2-adrenergic receptor haplotypes as an example.Semantic proximity Read ↗

Development and validation of the high-quality 'rapid method for swab' to genotype the HTTLPR serotonin transporter (SLC6A4) promoter polymorphism.Semantic proximity Read ↗

Tag SNP selection via a genetic algorithm.Semantic proximity Read ↗

Determination of human beta(2)-adrenoceptor haplotypes by denaturation selective amplification and subtractive genotyping.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.