Article
Association study of the NRAMP1 gene promoter polymorphism and early-onset type 1 diabetes.
Immunogenetics - 1 Jul 2002
Bassuny Wafaa M, Ihara Kenji, Matsuura Nobuo, Ahmed Saifuddin, Kohno Hitoshi, Kuromaru Ryuichi, Miyako Kenichi, Hara Toshiro
Abstract excerpt
Natural resistance-associated macrophage protein 1 (NRAMP1) has an important role in regulating macrophage functions that affect innate resistance as well as immune responses. We analyzed the microsatellite polymorphism in the promoter region of the human NRAMP1 gene in 206 type 1 diabetes patients and 200 normal children to determine whether this polymorphism might be associated with type 1 diabetes in the...
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