Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Myosin VI is required for E-cadherin-mediated border cell migration.

Nature cell biology - 1 Aug 2002

Geisbrecht Erika R, Montell Denise J

Abstract excerpt

Myosin VI (MyoVI) is a pointed-end-directed, actin-based motor protein, and mutations in the gene result in disorganization of hair cell stereocilia and cause deafness in mice. MyoVI also localizes to the leading edges of growth-factor-stimulated fibroblast cells and has been suggested to be involved in cell motility. There has been no direct test of this hypothesis, however. Drosophila melanogaster MyoVI is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Armadillo Domain Proteins
Share to beta Catenin
Share to Cadherins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cytoskeletal Proteins

Share to Insect Proteins

Share to Molecular Motor Proteins

Share to Myosin Heavy Chains

Source

Identifiers

PMID: 12134162
DOI: 10.1038/ncb830

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Myosin VI is required for E-cadherin-mediated border cell migration.PMID 12134162Read ↗

Myosin VI plays a role in cell-cell adhesion during epithelial morphogenesis.Semantic proximity Read ↗

Lessons from border cell migration in the <i>Drosophila</i> ovary: A role for myosin VI in dissemination of human ovarian cancerSemantic proximity Read ↗

Vezatin, a novel transmembrane protein, bridges myosin VIIA to the cadherin-catenins complex.Semantic proximity Read ↗

Invasive cell migration is initiated by guided growth of long cellular extensions.Semantic proximity Read ↗

Myosin VI is required for structural integrity of the apical surface of sensory hair cells in zebrafish.Semantic proximity Read ↗

Filopodia formation and endosome clustering induced by mutant plus-end-directed myosin VI.Semantic proximity Read ↗

Characterization of Myosin-IA and Myosin-IB, Two Unconventional Myosins Associated with theDrosophilaBrush Border CytoskeletonSemantic proximity Read ↗

Myosin Vb mediated plasma membrane homeostasis regulates peridermal cell size and maintains tissue homeostasis in the zebrafish epidermis.Semantic proximity Read ↗

The breathless FGF receptor homolog, a downstream target of Drosophila C/EBP in the developmental control of cell migration.Semantic proximity Read ↗

Vestigial is required during late-stage muscle differentiation in Drosophila melanogaster embryos.Semantic proximity Read ↗

Restoration of cytoskeletal and membrane tethering defects but not defects in membrane trafficking in the intestinal brush border of mice lacking both myosin Ia and myosin VI.Semantic proximity Read ↗

Asymmetric distribution of myosin IIB in migrating endothelial cells is regulated by a rho-dependent kinase and contributes to tail retraction.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.