Article
Myosin Vb mediated plasma membrane homeostasis regulates peridermal cell size and maintains tissue homeostasis in the zebrafish epidermis.
PLoS genetics - 1 Sept 2014
Sonal, Sidhaye Jaydeep, Phatak Mandar, Banerjee Shamik, Mulay Aditya, Deshpande Ojas, Bhide Sourabh, Jacob Tressa, Gehring Ines, Nuesslein-Volhard Christiane, Sonawane Mahendra
Abstract excerpt
The epidermis is a stratified epithelium, which forms a barrier to maintain the internal milieu in metazoans. Being the outermost tissue, growth of the epidermis has to be strictly coordinated with the growth of the embryo. The key parameters that determine tissue growth are cell number and cell size. So far, it has remained unclear how the size of epidermal cells is maintained and whether it contributes towards...
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