Article
Bovine leukemia virus SU protein interacts with zinc, and mutations within two interacting regions differently affect viral fusion and infectivity in vivo.
Journal of virology - 1 Aug 2002
Gatot Jean-Stéphane, Callebaut Isabelle, Van Lint Carine, Demonté Dominique, Kerkhofs Pierre, Portetelle Daniel, Burny Arsène, Willems Luc, Kettmann Richard
Abstract excerpt
Bovine leukemia virus (BLV) and human T-cell lymphotropic virus type 1 (HTLV-1) belong to the genus of deltaretroviruses. Their entry into the host cell is supposed to be mediated by interactions of the extracellular (SU) envelope glycoproteins with cellular receptors. To gain insight into the mechanisms governing this process, we investigated the ability of SU proteins to interact with specific ligands. In...
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