Article
Elongation of hair cell stereocilia is defective in the mouse mutant whirler.
The Journal of comparative neurology - 12 Aug 2002
Holme Ralph H, Kiernan Brent W, Brown Steve D M, Steel Karen P
Abstract excerpt
The recessive mouse mutant whirler (wi) shows no response to sound and exhibits circling and head-tossing behaviour, indicative of both auditory and vestibular dysfunction. The wi mutation maps genetically to mouse chromosome 4. We examined the organ of Corti of whirler mutants to explore the possibility that the wi mutation affects sensory hair cells. Scanning electron microscopy (SEM) reveals that the...
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