Article
Changes in flip/flop splicing of astroglial AMPA receptors in human temporal lobe epilepsy.
Epilepsia - 1 Jan 2002
Seifert Gerald, Schröder Wolfgang, Hinterkeuser Stefan, Schumacher Thekla, Schramm Johannes, Steinhäuser Christian
Abstract excerpt
PURPOSE: Recent data suggested a role for glial cells in epilepsy. This study sought to identify and functionally characterize AMPA receptors expressed by astrocytes in human hippocampal tissue resected from patients with intractable temporal lobe epilepsy. METHODS: Patch-clamp and fast application methods were combined to investigate astrocytes in situ and after fresh isolation from the stratum radiatum of the...
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