Article
CD80 (B7-1) and CD86 (B7-2) genes and genetic susceptibility to coeliac disease.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Aug 2002
Woolley N, Holopainen P, Bourgain C, Mustalahti K, Collin P, Mäki M, Partanen J
Abstract excerpt
The role of the costimulatory molecules B7-1 (CD80) and B7-2 (CD86) in T-cell activation makes them good candidates for coeliac disease susceptibility genes. We conducted a genetic linkage study of the CD80/86 gene region in the general Finnish population and in a local subisolate. No linkage was found in either population.
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