Article
Candidate genes colocalized to linkage regions in inflammatory bowel disease.
Digestion - 1 Jan 2002
Martin K, Radlmayr M, Borchers R, Heinzlmann M, Folwaczny C
Abstract excerpt
BACKGROUND/AIMS: The genes encoding for tumor necrosis factor-alpha (TNF-alpha), epidermal growth factor receptor (EGFR) and the vitamin D receptor (VDR) are colocalized to inflammatory bowel disease-associated linkage regions on chromosomes 6, 7 and 12. An association study of these gene polymorphisms with ulcerative colitis or Crohn's disease and a stratification according to disease phenotypes was performed in...
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