Article
A chemical approach towards understanding the mechanism and reversal of drug resistance in Plasmodium falciparum: is it viable?
IUBMB life - 1 Jan 2000
Chibale Kelly
Abstract excerpt
Genetic and biochemical approaches to studies of drug resistance mechanisms in Plasmodium falciparum have raised controversies and contradictions over the past several years. A different and novel chemical approach to this important problem is desirable at this point in time. Recently, the molecular basis of drug resistance in P. falciparum has been associated with mutations in the resistance genes, Chloroquine...
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