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Article

Reduced apoptosis and increased lesion development in the flow-restricted carotid artery of p75(NTR)-null mutant mice.

Circulation research - 20 Sept 2002

Kraemer Rosemary

Abstract excerpt

Apoptosis of neointimal smooth muscle cells is a well-recognized component of the pathogenesis of vascular lesions. In recent studies, we have identified the neurotrophin receptor, p75(NTR), as a mediator of apoptosis of neointimal smooth muscle cells. Neurotrophin ligands and p75(NTR) are selectively expressed in areas of atherosclerotic lesions with increased smooth muscle cell apoptosis and the neurotrophins...

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Source

Identifiers

PMID: 12242267
DOI: 10.1161/01.res.0000035245.83233.2a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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