Article
No evidence for phenotypic variation between probands in case-control versus family-based association studies of schizophrenia.
American journal of medical genetics - 8 Jul 2002
Malhotra Anil K, Bates John A, Jaeger Judith, Petrides Georgios, Robinson Delbert G, Bilder Robert M, Nassauer Katharine W
Abstract excerpt
Traditional case-control genetic association studies utilizing unrelated probands are often used interchangeably with family-based designs to detect genes for complex psychiatric disorders. This strategy may be limited, however, if significant phenotypic variation exists between probands enrolled in these two types of studies. The present study compared 37 probands enrolled in a case-control study of...
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