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Article

Herpesviruses in brain and Alzheimer's disease.

The Journal of pathology - 1 Jul 2002

Lin Woan-Ru, Wozniak Matthew A, Cooper Robert J, Wilcock Gordon K, Itzhaki Ruth F

Abstract excerpt

It has been established, using polymerase chain reaction (PCR), that herpes simplex virus type 1 (HSV1) is present in a high proportion of brains of elderly normal subjects and Alzheimer's disease (AD) patients. It was subsequently discovered that the virus confers a strong risk of AD when in brain of carriers of the type 4 allele of the apolipoprotein E gene (apoE-epsilon4). This study has now sought, using PCR,...

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Identifiers

PMID: 12115887
DOI: 10.1002/path.1127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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