Article
Polymorphisms of DNA repair gene XRCC3 Thr241Met and risk of gastric cancer in a Chinese population.
Cancer letters - 31 Mar 2004
Shen Hongbing, Wang Xinru, Hu Zhibin, Zhang Zhengdong, Xu Yaochu, Hu Xu, Guo Jiantao, Wei Qingyi
Abstract excerpt
Mammalian cells are constantly exposed to a wide variety of genotoxic agents from both endogenous and exogenous sources. Genetic variability in DNA repair may contribute to human cancer risk. In this population-based case-control study in China, we tested the hypothesis that a C to T variant (Thr241Met) of DNA repair gene XRCC3 (X-ray repair cross-complementing group 3) is associated with risk of developing...
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