Article
A gene in the telomeric HLA complex distinct from HLA-A is involved in predisposition to juvenile idiopathic arthritis.
Arthritis and rheumatism - 1 Jun 2002
Smerdel Anna, Lie Benedicte A, Ploski Rafal, Koeleman Bobby P C, Førre Øystein, Thorsby Erik, Undlien Dag E
Abstract excerpt
OBJECTIVE: Juvenile idiopathic arthritis (JIA) is associated with particular alleles at 3 different HLA loci: HLA-A, HLA-DR/DQ, and HLA-DP. These associations are independent of each other (i.e., they cannot be explained by the known linkage disequilibrium between alleles at these loci). The purpose of this study was to look for additional JIA susceptibility genes in the HLA complex. METHODS: One hundred two...
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