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Article

Association between tyrosine hydroxylase polymorphisms and left ventricular structure in young normotensive men.

British journal of biomedical science - 1 Jan 2002

Linhart Ales, Jindra Antonín, Golán Lubor, Jáchymová Marie, Sedlácek Kamil, Peleska Jan, Umnerová Vera, Bultas Jan, Horký Karel, Aschermann Michael

Abstract excerpt

Tyrosine hydroxylase (TH) is a rate-limiting enzyme for catecholamine biosynthesis. Increased sympathetic activity is associated with an increased left ventricular (LV) mass. However, the influence of TH gene polymorphisms on LV structure and function has yet to be investigated. Here, we analyse the association of Val-81-Met and tetranucleotide TCAT repeat TH polymorphisms with LV structure and function (assessed...

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Share to Genetic Predisposition to Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

Share to Tyrosine 3-Monooxygenase

Share to Ventricular Function, Left

Source

Identifiers

PMID: 12113410

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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