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Article

Analysis of p53 mutations and Helicobacter pylori infection in human and animal models.

Journal of gastroenterology - 1 Jan 2002

Murakami Kazunari, Fujioka Toshio, Kodama Masaaki, Honda Shoji, Okimoto Tadayoshi, Oda Touta, Nishizono Akira, Sato Ryugo, Kubota Toshihiro, Kagawa Jiro, Nasu Masaru

Abstract excerpt

BACKGROUND: p53 gene mutations are believed to play a critical role in the development of gastric carcinoma. We examined the relation between Helicobacter pylori infection and p53 gene mutations of the gastric mucosa in human and animal models. METHODS: To detect the original p53 DNA sequences of the Japanese monkey and Mongolian gerbil, the p53 genes of these animals were amplified using the nested polymerase...

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PMID: 12109656
DOI: 10.1007/BF02990091

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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