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Article

Sex differences in models of temporal lobe epilepsy: role of testosterone.

Brain research - 19 Jul 2002

Mejías-Aponte Carlos A, Jiménez-Rivera Carlos A, Segarra Annabell C

Abstract excerpt

Kainic acid and pilocarpine were used to assess sex differences in temporal lobe seizures. Adult Sprague-Dawley rats were injected with kainic acid (10-12 mg/kg) or with pilocarpine (380 mg/kg) and behavior was recorded for the next 3 h. Trunk blood was collected for hormonal measurements. Our data indicate that the male is more susceptible to the convulsant effects of agents that produce temporal lobe-like...

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Source

Identifiers

PMID: 12106683
DOI: 10.1016/s0006-8993(02)02691-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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