Article

Ferulic Acid Inhibits Catamenial Epilepsy Through Modulation of Female Hormones

2021-08-11

Abstract excerpt

Approximately 40% of women with epilepsy experience perimenstrual seizure exacerbation, referred to as catamenial epilepsy. These seizures result from cyclic changes in circulating progesterone and estradiol levels and there is no effective treatment for this form of intractable epilepsy. We artificially increased progesterone levels and neurosteroid levels (pseudo-pregnancy) in adult Swiss albino female mice (19-...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 171e6f31-d34a-5de6-b2e0-3791c5f8c206
DOI: 10.21203/rs.3.rs-728662/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Ferulic Acid Inhibits Catamenial Epilepsy Through Modulation of Female HormonesDOI 10.21203/rs.3.rs-728662/v1Read

Animal models in EpilepsySemantic proximity Read

Ovarian cycle-linked changes in GABA(A) receptors mediating tonic inhibition alter seizure susceptibility and anxiety.Semantic proximity Read

Flowers for Algernon: steroid dysgenesis, epigenetics and brain disorders.Semantic proximity Read

Female-Specific Pituitary Hypersensitivity to Gonadotropin-Releasing Hormone in a Mouse Model of Chronic Temporal Lobe EpilepsySemantic proximity Read

Sex hormones and risk of epilepsy: A bidirectional Mendelian randomization studySemantic proximity Read

Lateralized phenotypic differences after intrahippocampal kainic acid injection in female miceSemantic proximity Read

Epilepsy in Pregnancy—Management Principles and Focus on ValproateSemantic proximity Read

Expanding the therapeutic potential of neuro(active)steroids: a promising strategy for hyperdopaminergic behavioral phenotypes.Semantic proximity Read

Evaluating the interplay between estrous cyclicity and induced seizure susceptibility in <i> Scn2a <sup>K1422E</sup> </i> miceSemantic proximity Read

WITHDRAWN: Astaxanthin improved carbamazepine efficacy and mood comorbidities in epileptic rats through GABAergic signaling pathway enhancementSemantic proximity Read

Allopregnanolone and progesterone in relation to a single electroconvulsive therapy seizure and subsequent clinical outcome: an observational cohort studySemantic proximity Read

Rats bred for susceptibility to depression-like phenotypes have higher kainic acid-induced seizure mortality than their depression-resistant counterparts.Semantic proximity Read