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Article

HIV-1 infection of DC: evidence for the acquisition of virus particles from infected T cells by antigen uptake mechanism.

PloS one - 15 Oct 2009

Venkatachari Narasimhan J, Alber Sean, Watkins Simon C, Ayyavoo Velpandi

Abstract excerpt

Dendritic cells (DC) play a pivotal role in transmission and dissemination of HIV-1. Earlier studies reported that DC present at the site of infection trap virus particles via DC-SIGN and transfer the virus to the interacting naïve T cells. This prompted us to ask the question whether DC could acquire virus from infected T cells during DC-T cell interaction. To address this, we investigated the likely transfer of...

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Share to CD4-Positive T-Lymphocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dendritic Cells

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Source

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Identifiers

PMID: 19829715
DOI: 10.1371/journal.pone.0007470
PMCID: PMC2759578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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